American Nurses Credentialing Center (ANCC) Practice Exam 2025 - Free ANCC Practice Questions and Study Guide

In the case of a 16-year-old diagnosed with both mononucleosis and a streptococcal infection, the most suitable medication is erythromycin. This antibiotic is particularly relevant because patients with mononucleosis, which is often caused by the Epstein-Barr virus, can develop complications such as a streptococcal throat infection.

Key factors for choosing erythromycin include its effectiveness against streptococcal bacteria and its safety profile for use in patients who may have a penicillin allergy or sensitivity, which is an important consideration since amoxicillin, another common antibiotic for streptococcal infections, can have complications in these scenarios. Unlike amoxicillin, erythromycin is not associated with a rash often experienced by those with mononucleosis, which further supports its use.

Doxycycline is generally used for different infections and is less effective against streptococcal bacteria compared to erythromycin. Trimethoprim-sulfamethoxazole is also not the first-line treatment for streptococcal infections and would not be the ideal choice in this situation. Thus, erythromycin is the most appropriate medication in this context due to its targeted action against the streptococcal infection and