American Nurses Credentialing Center (ANCC) Practice Exam 2025 - Free ANCC Practice Questions and Study Guide

Lorazepam, a benzodiazepine, is associated with an increased risk of confusion and delirium, particularly in older adults. This population often has altered pharmacokinetics and pharmacodynamics due to age-related changes in metabolism, which can lead to prolonged effects of the medication. Benzodiazepines can cause sedation and impair cognitive function, making them riskier for elderly patients who may already be dealing with cognitive decline or other neurological issues.

The potential for adverse effects like confusion and delirium is significant because these outcomes can increase the risk of falls, accidents, and further decline in mental status in older adults. Consequently, healthcare providers are usually advised to use lorazepam with caution, carefully weighing the benefits against the risks in this demographic.

Other medications listed may also have considerations for use in older adults, but lorazepam is particularly highlighted for its profound impact on cognitive function and mental status.